Autologous stem cell transplantation in patients with extragonadal germ cell tumors: A single center experience

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Autologous Stem Cell Transplantation for Transformed Lymphoma: Single-Center Experience

ABSTR ACT: This is a single-center review of retrospectively collected computerized data and medical records of all the patients who have undergone high dose chemotherapy and ASCT for transformed lymphoma from 1999–2014. The primary endpoint of the study was overall survival (OS) and secondary endpoint was progression free survival (PFS). A total of 27 patients with histological transformation ...

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Extragonadal germ cell tumors.

Germ cell cancer is the most common malignancy in men aged 15–35 years; 5% of the malignant germ cell tumors are of extragonadal origin [1]. An extragonadal germ cell tumor (EGGCT) is by definition a germ cell neoplasm displaying one of the histologies associated with gonadal origin, but located outside of the gonads. This specific clinical entity was first described in the 19th century [2, 3]....

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Hodgkin’s Lymphoma Occurring Secondary to Autologous Stem Cell Transplantation in Plasma Cell Leukemia; A Case Report

Survival of patients with multiple myeloma has improved substantially because of availability of new therapies including autotransplants, immunomodulating drugs and proteasome-inhibitors. Second primary cancers have emerged as an important determinant of morbidity and mortality among cancer survivors. Even though there is an increased risk of new cancers of the lymphoreticular and haematopoetic...

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Cytomegalovirus Reactivation in Adult Recipients of Autologous Stem Cell Transplantation: a Single Center Experience

INTRODUCTION Cytomegalovirus (CMV) reactivation and infection are well-recognized complications after allogeneic stem cell transplantation (SCT). Only a few studies have addressed CMV reactivation after autologous SCT (ASCT). METHODS We retrospectively reviewed medical records of 210 adult patients who underwent ASCT for lymphoma or multiple myeloma (MM) at a single center from January 1(st),...

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Should extragonadal germ cell tumors be included in studies of families with testicular germ cell tumors?

BACKGROUND Family history is among the few established risk factors for testicular germ cell tumor (TGCT). Approximately 1.4% of newly diagnosed TGCT patients report a positive family history of TGCT. Sons and siblings of TGCT patients have four- to six fold and eight- to tenfold increase in TGCT risk, respectively. In twins of men with TGCT the relative risk of testicular cancer is 37.5 (12.3-...

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ژورنال

عنوان ژورنال: Gulhane Medical Journal

سال: 2020

ISSN: 1302-0471,2146-8052

DOI: 10.4274/gulhane.galenos.2019.899